Neonatal meningitis at National Hospital Cayetano Heredia from Perú
DOI:
https://doi.org/10.61651/rped.2008v61n3p157-164Keywords:
Meningitis, Infant, Newborn, Cerebrospinal Fluid, EncephalitisAbstract
Introduction: Neonatal meningitis is a prevalent problem in the neonatal units. Objective: To determine the frequency and clinical and laboratory characteristics of patients with neonatal meningitis from january 2003 to december 2007. Material and Methods: The database of the unit of intensive neonatal care, the one of the unit of intermediate cares and the database of neonatal neurology were revised. The cases were classified in precocious and late forms and it was registered the demographic, clinical and laboratory data. Results: 24 newborn were included, they determined a prevalence of 0.9 cases per thousand born alive. The precocious form was the most frequent. The germ was isolated in 46% of the cases, more frequent in the early form. 92% of the newborns were symptomatic, the fever and irritability were the most frequent symptoms. The most related risk factors were premature membranes rupture and maternal fever during labor. The cerebrospinal liquid showed moderate pleocitosis with wide variability, with polimorfonuclears preponderance prevalence in the early form, it was also observed a higher grade in hypoglicorrachia and hyperproteinorrachia in the same form. The letality was of 25%. Conclusions: Neonatal meningitis has a high prevalence, it was very symptomatic and it presented moderate to severe changes in the cerebrospinal liquid.
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