Neonatal acute pain with repeated painful stimuli, randomized trial comparing three analgesic non pharmacological methods

Authors

  • Gustavo Rivara Dávila Hospital Nacional Arzobispo Loayza, Lima Peru
  • Sonia Huaipar Rodríguez Hospital Nacional Arzobispo Loayza, Lima Perú
  • Debbie Miyasato Higa Hospital Nacional Arzobispo Loayza, Lima Peru
  • Cynthia Liu Bejarano Hospital Nacional Arzobispo Loayza, Lima Peru
  • Diego Briceño Clemens
  • Andrea Bucher Oliva
  • Ximena de Noriega Madalengoitia
  • Sandra Viale Paez
  • Patrick Pendavis Heksner
  • Pamela García-Corrochano Medina
  • Gabriela García Nores
  • Miguel Juárez Salcedo
  • Fiorella Iglesias Cárdenas
  • Carmen Medina Quiñones
  • Carlos Herrera Tipacti

DOI:

https://doi.org/10.61651/rped.2009v62n1p08-14

Keywords:

Pain

Abstract

Introduction: Non pharmacological methods are rarely used in neonatal units. repeated painful stimuli have long noxious effects.

Objective: To verify the effectiveness of non pharmacological methods in repeated painful procedures; to determine which method is more effective.

Material and methods: We conducted a randomized controlled trial. Newborns were randomly assigned into 3 groups (n=40 per group). All of them underwent painful procedures during the first 3 days of life (hepatitis B, BCG and blood sample for determine group and factor). Group A received breast feeding and skin to skin contact as non pharmacological method during the painful stimuli, group B received dextrose 10% and group C only suction. Douleur Aigue Nouveau-ne scores (DAN, Carvajal et al.) and ABC scale (Bellieni et al.) were used to assess neonatal pain. The 3 groups were compared in each stimulus to determine the most effective method, and the effectiveness in repeated painful stimuli.

Results: Group B showed the most analgesic effect in the 3 stimuli, with 97, 5% for NO PAIN vs. 87, 5% (A) and 85% (C) (p<0,036) with ABC scale, and 95% vs. 85% (A) and 70% (C) for NO PAIN with DAN scale (p<0,022). This difference was constant with all categories of pain. We observed that analgesic effect is greater in repeated painful stimuli. NO PAIN category was 70% in group B in the first stimuli, 85% in the second and 95% in third (p<0,020). This effect was also observed in groups A and C.

Conclusions: Dextrose 10% seems to offer the best analgesic effect compared with breast feeding and suction. Non pharmacological methods studied increase their effectiveness in repeated painful stimuli.

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Published

2009-12-31

How to Cite

1.
Rivara Dávila G, Huaipar Rodríguez S, Miyasato Higa D, Liu Bejarano C, Briceño Clemens D, Bucher Oliva A, et al. Neonatal acute pain with repeated painful stimuli, randomized trial comparing three analgesic non pharmacological methods. Rev Peru Pediatr [Internet]. 2009 Dec. 31 [cited 2024 May 14];62(1):08-14. Available from: https://pediatria.pe/index.php/pedperu/article/view/357

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ORIGINAL ARTICLE

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