Systemic onset juvenile idiopathic arthritis as paraneoplastic syndrome of diffuse astrocytoma
DOI:
https://doi.org/10.61651/rped.2024v76n3p2c1-7Keywords:
Systemic onset juvenile idiopathic arthritis, diffuse astrocytoma, paraneoplastic síndrome.Abstract
Objective: We report the case of an 8yeargirl boy with systemic onset juvenile idiopathic arthritis (JIA) as a paraneoplastic syndrome of a diffuse astrocytoma.
Materials and Methods: Review of clinical history, paraclinical, ultrasound, and brain MRI, brain biopsy and immunohistochemistry.
Case report: The patient presented with symptoms of JIA for 2 years, with adenopathy, fever, asthenia, and oligoarthralgias, which did not respond to conventional treatment. Three months before admission, he developed facial asymmetry and right hemiparesis. Magnetic resonance imaging revealed a 6x4 cm brain lesion affecting several structures. Partial resection of the tumor was performed and a diagnosis of diffuse astrocytoma grade II was made. Subsequently, the patient received chemotherapy, achieving remission of arthralgias and improvement in hemiparesis.
Conclusion: This is the first reported case of JIA associated with diffuse astrocytoma. It underlines the importance of excluding other pathologies in the diagnosis of JIA to ensure timely treatment.
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Copyright (c) 2024 Danny Asparrin Ramos, Roxana Díaz Subauste, Giancarlo Alvarado-Gamarra, Raquel Garcés Ghilardi, Matilde Estupiñan Vigil, Miriam Salas Olórtegui
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