Late clamping and intraventricular hemorrhage in premature newborns: A Systematic review and meta-analysis

Authors

  • Víctor Sánchez-Reyna
  • K. Polo
  • J. Portales - Armas
  • O. Quilcat
  • C. Quiliche
  • M. Quiñones - Cerna
  • P. Quispe

DOI:

https://doi.org/10.61651/rped.2021v73n1p09-17

Keywords:

Infant, Premature, Umbilical Cord, Cerebral Intraventricular Hemorrhage

Abstract

Objective: To compare the efficacy of late clamping (CT) compared to early clamping of premature newborns in the incidence of Intraventricular Hemorrhage (IVH).

Material and Methods: A bibliographic search was carried out in Pubmed, Medline and central Cochrane, the selected articles were stored in the Mendeley Computer Program, the RCTs were evaluated using the Cochrane risk of bias tool. The critical reading tool was the CASPe instrument and the GRADE system was used to assess the quality of the evidence. The Mantel-Hanzel method and the metabolin and metacontent functions of the R.3.5.1 metalibrary (www.r-project.or) were also used.

Results: In 10 studies, 7660 participants were registered. The mean / median gestational age in TC weeks ranged from 24.41.2 to 33.62.2. The highest and lowest average birth weights of newborns subjected to CT were 2030.2g and 645g, while for those who underwent early clamping it was 1.916g and 634g, respectively. Compared with early clamping, CT did not show a decrease in HIV cases in preterm infants. Subgroup analysis was performed with 32 weeks as the cut-off point. Similarly, it occurred in preterm infants less than 32 weeks.

Conclusion: There is a lower frequency of HIV in premature infants with TC compared to newborn with early clamping. All four grades of HIV were present in both groups.

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Published

2021-12-31

How to Cite

1.
Sánchez-Reyna V, Polo K, Portales - Armas J, Quilcat O, Quiliche C, Quiñones - Cerna M, et al. Late clamping and intraventricular hemorrhage in premature newborns: A Systematic review and meta-analysis. Rev Peru Pediatr [Internet]. 2021 Dec. 31 [cited 2025 May 16];73(1):09-17. Available from: https://pediatria.pe/index.php/pedperu/article/view/322

Issue

Vol. 73 Num. 1 (2021)

Section

ORIGINAL ARTICLE

Categories

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