EARLY CAFFEINE CITRATE THERAPY AND HOSPITAL STAY IN VERY LOW WEIGHT PREMATURE NEWBORNS
DOI:
https://doi.org/10.61651/rped.2025v77n1p3-9Keywords:
Infant, Premature, Infant, Very Low Birth Weight, CaffeineAbstract
Objective: Determine if there is an association between early therapy with caffeine citrate and hospital stay in very low birth weight premature neonates. Material and methods: A retrospective, case-control study was carried out. 118 very low weight premature newborns were included, comparing the length of hospital stay between premature infants who received early therapy with caffeine citrate and those who did not receive it. Results: In the group of very low birth weight premature newborns who received early therapy with caffeine citrate, the hospital stay was 5.7 days less (p = 0.016) compared to the group that did not receive it. In addition, in the first subgroup of newborns from 28 to 30 weeks of gestational age, the hospital stay was 3.9 days less (p = 0.604), and in the second subgroup of newborns from 31 to 33 weeks of gestational age, the hospital stay 7.9 days less (p = 0.002) for the group that received treatment. Conclusion: There is an association between early caffeine citrate therapy and reduced hospital stay in very low birth weight premature infants, especially between 31 and 33 weeks of gestational age.
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Copyright (c) 2025 Silvana Marily Morales Novoa, Edwin Capristán Díaz
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