Elevated uric acid levels in obese adolescents
DOI:
https://doi.org/10.61651/rped.2012v65n1p33-37Keywords:
Uric Acid, Pediatric Obesity, AdolescentAbstract
Objectives: To determine the frequency of elevated uric acid levels in obese adolescents aged 10 to 17 years and their relationship with metabolics characteristics.
Materials and methods: We performed a descriptive study. It included 115 obese adolescents aged 10 to 17 years attending the service of Endocrinology at the Arzobispo Loayza Hospital which met the inclusion criteria. Was defined as elevated uric acid levels> 5.5 mg / dl. It took data on age, sex, weight, height, body mass index (BMI), blood pressure, glucose, HDL, LDL, triglycerides, total cholesterol and alanine aminotransferase. The value of p <0.05 was considered significant.
Results: The 33.9% of patients had uric acid levels above 5.5 mg /dl. 54.8% (63 patients) were male. The median age was 13 ± 2 years. Acanthosis nigricans and abdominal obesity were the most common features on physical examination of these patients with 87% and 97% respectively. Relationship was obtained with age (p <0.02) male sex (p<0.001), family history of diabetes (p<0.03), abdominal circumference (p<0.001), weight (p<0.001) and BMI (p<0.001).
Conclusions: These results suggest that uric acid levels are significantly increased in obese adolescents and is related to sex, body mass index, waist circumference and blood pressure.
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