Clinical and epidemiological characteristics of nosocomial bloodstream candidiasis in the Instituto Nacional de Salud del Niño
DOI:
https://doi.org/10.61651/rped.2012v65n2p59-67Keywords:
Candidiasis, Invasive, Sepsis, PediatricsAbstract
Introduction: Nosocomial infections (NI) Candida sp. increased morbidity and hospital mortality in the last decade. They represent the most common fungal infections in hospitalized patients and are the fourth most common cause of hematogenous IN in the United States of America.
Objective: To determine the clinical and epidemiological characteristics of hospitalized patients with bloodstream infections by Candida in the various departments of the National Institute of Child Health (INSN).
Methods: We reviewed the medical records of all patients with positive blood culture according to records of the Microbiology Unit of INSN from January to December 2009 and who met the inclusion criteria. For statistical analysis we used SPSS 11.10 for Windows.
Results: Candida albicans species were isolated in 71.7% of all samples, with C. parapsilosis the most common species (30%). The services that performed the most isolates were Surgery, ICU and Gastroenterology. Intrinsic risk factors were more frequent malnutrition and Candida colonization and between extrinsic previous use of broad spectrum antibiotics, use of central venous catheter, previous abdominal surgery and intubation with mechanical ventilation. Crude Mortality nosocomial candidemia in INSN was 45%.
Conclusion: Candida albicans species are becoming more frequently isolated in hospitals, with the extrinsic risk factors more frequently reported prior use of broad-spectrum antibiotic, nasogastric tubes, central venous catheter, previous abdominal surgery, parenteral nutrition Total intubation and mechanical ventilation.
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