Preeclampsia as an associated factor to the development of retinopathy of prematurity in very low birth weight infants, born at the National Hospital Cayetano Heredia between January 2005 and December 2011
DOI:
https://doi.org/10.61651/rped.2013v66n2p73-83Keywords:
Pre-Eclampsia, Infant, Premature, Retinopathy of Prematurity, Infant, Low Birth WeightAbstract
Objective: To determine if preeclampsia is an associated factor to the occurrence of retinopathy of prematurity (ROP) in very low birth weight infants.
Materials and methods: A retrospective cohort study of very low birth weight infants born in Hospital Cayetano Heredia between January 2005 and December 2011. The associated factors where analyzed by the bivariate analysis and as confounding factors in a logistic regression model.
Results: Two hundred fifty eight infants were eligible for the cohort. Mean gestational age was 30.92 ± 2.92 weeks and mean birth weight 1170.39 ± 252 grams. From the total, 96 (37%) had maternal history of preeclampsia and 162 (63%) did not. An incidence of ROP of 313 per 1,000 live births (31.3%) was found. The incidence of ROP in newborns of preeclamptic mothers was 282 per 1000 live births (28.2%) and in those with no history of preeclampsia was 329 per 1000 live births (32.9%). The relative risk for a history of preeclampsia was 1.28 with 95% CI 0.68 – 2.43 and a p value with no statistical significance (p = 0.448).
Conclusions: There was no statistically significant association between a history of maternal preeclampsia and the development of retinopathy of prematurity in this study.
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