Clinical Epidemiology Study of Cystic Fibrosis in the National Institute of Child Health, 2002-2011 Lima.

Abstract

Introduction: Cystic Fibrosis (CF) is an autosomal recessive disease that occurs primarily for their commitment in the lungs and digestive system. In Peru, the prevalence of CF is unknown as well as the clinical and epidemiological characteristics of the disease.

Objective: To determine the clinical and epidemiological characteristics of CF at National Institute of Child Health from 2008 to 2011.

Methods: We conducted a clinical epidemiological research which design is observational, retrospective and descriptive. Patient cases were selected from the National Institute of Child Health with diagnosis of the disease in their medical records, between January 2002 and December 2011.

Results: We recorded 37 cases that met the criteria for inclusion in the consensus of the American Foundation for CF. The ages ranged diagnostic from one month to 16 years, 51.4% being women. The main clinical features were predominantly respiratory and digestive, it was found out that 94.6% of patients had acute or chronic respiratory symptoms and 54.1% steatorrhea.

Conclusion: In all patients sinopulmomar disease was chronic, of which 75.7% had chronic productive cough. Gastrointestinal abnormalities occurred in 81.1% of patients, being growth a failure in all of them. The most common complication was pneumonia by 59.5%. The most common pathogen in the respiratory system was Staphylococcus aureus in 51.4%, followed by Pseudomonas aeruginosa in 48.6%.